GRAFIX PL◊ + GRAFIX◊ Placental Membranes
Most human tissue products feature only growth factors and an extracellular matrix. GRAFIX PL Lyopreserved and GRAFIX Cryopreserved Placental Membranes retain all three native components of human placental membranes, including native placental cells1
Human tissue for human wounds
Minimal manipulation to maximize retained components
Our human placental tissue products, carefully processed to minimize manipulation of the native tissue, are composed of native cells, growth factors and an intact extracellular matrix:
- Designed as wound covers for a wide variety of acute and chronic wounds in head-to-toe locations
- Flexible, conforming cover that may be applied to complex anatomies and may be used over exposed bone, tendon, joint capsule, muscle and hardware
- Two storage options are available:
- GRAFIX PL Membrane is lyopreserved and stored at room temperature for off-the-shelf convenience
- GRAFIX◊Cryopreserved Placental Membrane is stored at -75°C to -85°C
Product features
Application
Evidence and Case Studies
Medical Education
Reimbursement
For reimbursement and coverage information by state, click here.
Sizes and Ordering Information
| Placental tissue source | Product description | Part # |
| Lyopreserved amniotic membrane | GRAFIX PL XC 5 cm x 5 cm (25 cm2) | PS15055 |
| GRAFIX PL XC 7 cm x 7 cm (49 cm2) | PS15077 | |
| GRAFIX PL XC 7.5 cm x 15 cm (113 cm2) | PS15075 | |
| GRAFIX PL PRIME 1.5 cm x 2 cm (3 cm2) | PS13015 | |
| GRAFIX PL PRIME 2 cm x 3 cm (6 cm2) | PS13023 | |
| GRAFIX PL PRIME 3 cm x 3 cm (9 cm2) | PS13033 | |
| GRAFIX PL PRIME 3 cm x 4 cm (12 cm2) | PS13034 | |
| GRAFIX PL PRIME 5 cm x 5 cm (25 cm2) | PS13055 | |
| Lyopreserved chorion membrane | GRAFIX PLUS 2 x 3 cm (6 cm2) | PS16023 |
| GRAFIX PLUS 3 x 4 cm (12 cm2) | PS16034 | |
| Cryopreserved amniotic membrane | GRAFIX XC 7.5 cm x 15 cm (113 cm2) | PS24075 |
| GRAFIX PRIME 16 mm Disc (2 cm2) | PS60013 | |
| GRAFIX PRIME 1.5 cm x 2 cm (3 cm2) | PS11015 | |
| GRAFIX PRIME 2 cm x 3 cm (6 cm2) | PS11023 | |
| GRAFIX PRIME 3 cm x 4 cm (12 cm2) | PS11034 | |
| GRAFIX PRIME 5 cm x 5 cm (25 cm2) | PS11055 | |
| GRAFIX CORE 3 x 4 cm (12 cm2) | PS12034 | |
| GRAFIX CORE 5 x 5 (25 cm2) | PS12055 |
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Disclaimer
Always refer to the enclosed package insert for the complete application protocol. Smith+Nephew does not provide medical advice. The information presented is not, and is not intended to serve as, medical advice. For detailed information, including indications for use, contraindications, precautions and warnings, please consult the product’s package insert prior to use. It is the responsibility of healthcare professionals to determine and utilize the appropriate products and techniques according to their own clinical judgment for each of their patients.
Use of this Web site is governed by the Terms of Use, Copyright and Disclaimer and Privacy Policy. This website is intended for caregivers in the United States only. The information provided is for informational purposes only and is not intended to be medical advice. It does not replace the professional training, experience and knowledge of the healthcare provider responsible for patient care, who must base treatment upon the unique characteristics of each patient. Every patient’s case is unique and each patient should follow his or her doctor’s specific instructions. For detailed product information, including indications for use, contraindications, effects, precautions and warnings, please consult each product’s Instructions for Use (IFU) prior to use.
©2022 Smith+Nephew, Inc. All rights reserved.
GRAFIX and STRAVIX brands are trademarks of the product manufacturer Osiris Therapeutics, Inc. which is part of Smith & Nephew, Inc.
GRAFIX Customer Care: T 1-888-674-9551 F 443-283-4419
Advanced Wound Management Smith+Nephew, Inc.
Recall and Complaints
Customer will provide such support and assistance as S+N may reasonably request in the event of a general or limited voluntary or mandatory recall of the Product(s). Customer shall promptly report any complaint in respect of the Products to complaints@smith-nephew.com.
Citations
- Dhall S, et al. Plos One. 2018; 13 (10): e0204060
- Rodríguez-Ares MT, et al. Acta Ophthalmol. 2009; 87 (4): 396-403
- Lim LS, et al. Arch Ophthalmol. 2010; 128 (10): 1303-1310
- Niknejad H, et al. Cryobiology. 2011; 63 (3): 145-151
- Thomasen H, et al. Graefes Arch Clin Exp Ophthalmol. 2009; 247 (12): 1691-1700
- Diabetic foot problems: prevention and management. National Institute for Health and Care Excellence (NICE) guideline. Published: 26 August 2015. https://www.nice.org.uk/guidance/ng19
- Diabetic foot problems: prevention and management. National Institute for Health and Care Excellence (NICE) guideline. Published: January 2016. https://www.nice.org.uk/guidance/ng19/evidence/appendix-h-data-analysis-435358773, page 11
- Diabetic foot problems: prevention and management. National Institute for Health and Care Excellence (NICE) guideline. Published: January 2016. https://www.nice.org.uk/guidance/ng19/evidence/appendix-i-grade-profiles-15672915540